Me? I use Mozy (Of course) but for those ridiculously large files I'm not going to wait for my ADSL connection to upload I use SyncToy 2.0 for Windows.
SyncToy makes the copy to an external drive, Mozy scoops it up and moves it offline. I now have a fast local restore as well as an offsite copy. For any of you Macheads I'm sure there's an Automator Action somewhere which will do the same thing.
And if you use Linux you're using rsync anyway so nothing to see here. Move along.
